Origin
Welcome to SimTIVA blog. SimTIVA is a program which simulates the behaviour of a target-controlled infusion pump. It is similar to other existing programs, such as TIVA trainer on PC's, and iTIVA on smartphones. But the major differences are: SimTIVA is completely free; and also it can be run on any browser, on computers and smartphones. Origin of the project The idea started in October 2020, almost one year ago. At that time, I have already developed a paediatric calculator app, which has branched off into anaesthetist's and paediatric intensivist's versions (you can read more about the paediatric calculator project here ). I wanted to use the experience for something else, something more. The clinical question is like this. If you give propofol, after a bolus, it enters the bloodstream and will eventually reach the brain (the effect site) and exert its anaesthetic effect. The plasma concentration and the effect site concentration are expressed as CP and CE respectively