Changelog

This is a project in active development.

Last updated: 8 April, 2025

Version 5.1 (Build 143, Apr 2025) Current

  • RSI mode: facilitates RSI using TIVA. User entry of CE target, time to reach CE, and bolus speed. Infusion scheme with bolus size, pause time, with display of expected CE overshoot at peak.
  • Dexmedetomidine (Hannivoort model): CP/CE/Manual modes. Safety feature: bolus speed for loading dose (if any) is limited <6mcg/kg/h
  • Fullscreen mode bug fixes and visual improvements
  • CP targeting infusion scheme time delay bug fixed
  • Vertical (Y-axis) scale can now be adjusted

Version 5.0 (Build 125, Dec 2024)

  • UI/UX improvement: status bar with next change prompt for CPT/CET modes
  • UI/UX in iOS: optimized landscape display with compliance to "safe areas"
  • Performance improvements: deleted fontawesome-regular file and optimized loading times; division into smaller sections of CSS/JS files

Version 4.84 (Build 118, Oct 2024)

  • New feature: bolus speed - allow user entry of induction bolus speed in CPT/CET mode, from 300ml/h to 1200ml/h, or flash (instantaneous)
  • Bugfix: scheme generation bug in "share module"
  • Viewer app bugfixes
  • UI changes: options module layout changed

Version 4.81 (Build 111, Aug 2024)

  • Updated manual (v2.0) to add chapter on Advanced Features & Eleveld Emulation
  • Improved graph dimensions on computer/widescreen devices
  • Corrected minor issues (incorrect reference for pharmacodynamic interaction, arrow symbol in complex mode, bug on loading complex mode simfile)

Version 4.8 (Build 109, May 2024)

  • Feature: Emulation of Eleveld model when using Marsh/Schnider model
  • Feature: Adjusted body weight for Marsh & Schnider with information prompt
  • BW validation: only extreme BMI (e.g. BMI>=35) will trigger warning screen
  • UI/UX: Omitted the "I confirm" and "Disclaimer" check on front screen
  • Bugfixes: error in displaying model parameters after re-selecting a model

 Version 4.7 (Build 102, Mar 2024)

  •  Bugfixes: graph options, eBIS after pause
  •  Infusion duration increased to 6 hours (previously 2 hours)
  •  User Manual: initial release

 Version 4.6 (Build 100, Feb 2024) 

  • Model: Eleveld "without opioid" is added.
  • Control panel: controls the timeline. Quick reset: reset the infusion data. Pause: pause the simulation at current time instance. Jump: jump forward or backward in time

Version 4.5 (Build 97, Jan 2024) 

  • Updated the UI for CPT and CET modes with more compact interface design
  • Sophisticated "preview box" can be viewed by clicking "expand" - previews the full scheme ahead for CPT/CET modes
  • Corrected the CPT algorithm - previously, increasing CPT will overshoot the CP and decreasing the CPT will cause premature re-start of infusion
  • Improved support for widescreen devices particularly in complex/dual mode
  • Bugfix in Safari browser, MacOS

Version 4.4 (Dec 2023)

  • Bolus/Infusion unit function: manual mode - can change infusion unit from "ml/h" to "mg/kg/h" (or appropriate units) & change the bolus unit from "mg" to "mg/kg" or "ml" (or appropriate units)
  • Corrected algorithm in decremental infusion rates for reducing target in CET mode

Version 4.3 (Dec 2023)

  • "Quick edit CeT and CpT" in Fullscreen mode
  • Export/import module - sim-files can be exported to a .CSV file and imported back to SimTIVA or loaded into spreadsheet program. Contains individual weblinks for each sim to replay the sim in a browser.
  • Interface improvements: added ML in preview of CpT and CeT modes, labels of axes in chart
  • Pharmacology: bug fix for fentanyl

Version 4.1 (Nov 2023)

  • Fullscreen mode: Shows current infusion regimen (rates + bolus) in the graph over time; helps to visualize the relationship between CP/CE and changes in infusion dosing
  • UI/UX: iPhone user interface dramatically improved
  • Pharmacology: added alfentanil (Maitre)

Version 4.0 (Sep 2023)

  • Complex mode : two drug regimen and pharmacodynamic interaction using "PTOL" index - probability of tolerance to laryngoscopy 
  • eBIS for eleveld model: Ce propofol relates to estimated BIS based on PD modelling given by eleveld model
  • Improved chart functions: charts can now extend beyond the standard 20min limit as in the last version. The time axis can now be adjusted by user.
  • Paediatric mode: allows entry of age in days, weeks, or months; allows entry of postmenstrual age in premature kids (valid for <6month old infant for eleveld model- PMA will affect clearance)

Version 3.2 (Aug 2022)

  • Pharmacology: Added Fentanyl (Shafer) model, with or without weight adjustment according to formulas by Shibutani

Version 3.1 (May 2022)

  • Feature: "Share" module and separate Viewer App
  • Feature: "Save" functionality with automatically saving simfiles and ability to rescue the last saved simfile or to load previous simfiles
  • Feature: Added add/remove/edit events functionality

Version 3 (Jan 2022)

  • Feature: Time and volume estimation modules
  • Design: Dark mode theme
  • Design: Updated chart engine and related coding to ensure compatibility with ChartJS v3.7.1; this improves speed of charting 
Version 2.1 (Aug 2021)
  • Design: Improves display of CP, CE and infusion rate on top bar of screen
  • Feature/Design: Added screen wake-lock function (screen always on when app active) (supported device only)

Version 2 (Jul 2021)

  • Feature: Added wake-up time (decrement time) prediction module
  • Feature: Added data validation, prompting for invalid model, BMI and weight validation for data input
  • Feature: Added device notification and sound notification (supported device only)
  • Feature: Added remifentanil models (Minto, Eleveld)

Version 1 (Feb 2021)

  • Feature: Added CET mode
  • Feature: Added retrospective correction module
  • Pharmacology: Added Eleveld model and Paedfusor model for propofol
  • Design: responsive design and allow appropriate display on landscape and portrait screen orientation across all screen sizes

Version 0.1 (Nov 2020)

  • Initial release
  • CPT mode and manual mode available
  • Marsh, Schnider models available


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